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Maggie A. DiGuardo, M.D.

  1. Pathologist
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Publications

  1. Strader SR, Smither FC, Klein MS, Wiltshire TD, Jacob EK, Levine BL, DiGuardo MA. Urgent need for physician education in cell and gene therapy. Transfusion. 2026 Jul 19 Epub 2026 July 19
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  2. Abdelmagid M, Hashi NJ, Hefazi M, Matin A, Gauto Mariotti E, Hogan WJ, Litzow MR, Alkhateeb HB, Shah MV, Durani U, Kenderian SS, Foran JM, Murthy HS, Kharfan-Dabaja MA, Roy V, Ayala E, Patnaik MM, Dingli D, DiGuardo MA, Jacob EK, Mangaonkar AA. Comparative Efficacy of Donor Lymphocyte Infusions in Augmenting Graft-versus-Leukemia Effect after Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Myeloid Malignancies. Acta Haematol. 2026 Jun 8; 1-9 Epub 2026 June 08
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  3. Strader S, Medlyn M, Klein M, DiGuardo M, Arthurs J, Shapiro S. Introduction to Translating Orthobiologics and Cellular Therapies for the Musculoskeletal Provider. Am J Phys Med Rehabil. 2026 Apr 1; 105 (4):363-369
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  4. Wang Y, McKenna D, Spitzer T, Brunker P, Nedelcu E, Fesnak A, Celluzzi C, DiGuardo M, Jacob EK. Training in cell and gene therapy manufacturing: Unmet needs and arguments for graduate medical education. Transfusion. 2026 Jan; 66 (1):259-265 Epub 2025 Dec 23
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  5. Kanwar N, Campion MB, Schneider AR, Milosevic D, Sosa C, Wojcik AA, Halling KC, Rumilla KM, Lo YC, Niu Z, Geiersbach KB, DiGuardo MA, Kipp BR, Zheng G. Validation and Clinical Utility of a Pan-Cancer Circulating Tumor DNA Assay as a First-Approach Test. J Mol Diagn. 2025 Dec; 27 (12):1213-1223 Epub 2025 Sept 25
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  6. Sterner RM, Sherani F, DiGuardo MA, Greipp PT, Moyer AM. An Ambiguous NUDT15 Signal in a Child with B-cell Acute Lymphoblastic Leukemia. Clin Chem. 2025 Aug 1; 71 (8):835-839
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  7. Krull AA, DiGuardo MA, Deeds MC, Skaer CA, Soiney KA, Wadewitz M, Wiltshire TD, Gastineau DA, Dietz AB, Jacob EK. Fellowship training for cellular therapy laboratory directors. Cytotherapy. 2025 May; 27(5):642-648. Epub 2025 Jan 29.
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  8. Sterner RM, Strasburg DJ, Va S, DiGuardo MA, Jacob EK. A three-step method for preparing cryopreserved samples of apheresis products for post-thaw analysis yields a high recovery of viable cells. Transfusion. 2024 Dec; 64 (12):2341-2344 Epub 2024 Nov 07
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  9. Strasburg DJ, Sterner RM, Va S, Jacob EK, DiGuardo MA. A 3-step method for preparing cryopreserved samples of apheresis products for post-thaw analysis yields a higher percentage of viable cells. Transfusion. 2024 May; 64 (5):866-870 Epub 2024 Apr 12
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  10. Abels E, Adkins BD, Allen ES, Booth GS, DiGuardo MA, Ding JJ, Guarente J, Klein M, Stephens LD, Tormey CA, Woo JS, Jacobs JW. Updates in the care of the alloimmunized pregnant patient: A transfusion medicine and clinical laboratory perspective. Am J Clin Pathol. 2023 Nov 02; 160(5):441-443.
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  11. Thompson TZ, Krull AA, Strasburg DJ, Adamski J, Jacob EK, DiGuardo MA. Collection and processing of hematopoietic progenitor cell products at risk of presenting with cold agglutination. Cytotherapy. 2023 Jul; 25 (7):699-703 Epub 2023 Apr 10
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  12. Krull A, Thompson T, Strasburg D, DiGuardo M, Jacob EK. How do I warm HPC(A) products to maximize cell viability in the setting of cold agglutinin disease? Transfusion. 2022 Oct; 62 (10):1942-1947 Epub 2022 Aug 10
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  13. Tauscher C, Moldenhauer S, Bryant S, DiGuardo M, Jacob EK. Antibody incidence and red blood cell transfusions in patients on daratumumab. Transfusion. 2021 Dec; 61(12):3468-3472. Epub 2021 Oct 07.
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  14. Sankaranarayanan S, Balan J, Walsh JR, Wu Y, Minnich S, Piazza A, Osborne C, Oliver GR, Lesko J, Bates KL, Khezeli K, Block DR, DiGuardo M, Kreuter J, O'Horo JC, Kalantari J, Klee EW, Salama ME, Kipp B, Morice WG, Jenkinson G. COVID-19 Mortality Prediction From Deep Learning in a Large Multistate Electronic Health Record and Laboratory Information System Data Set: Algorithm Development and Validation. J Med Internet Res. 2021 Sep 28; 23(9):e30157.
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  15. Juskewitch JE, Tauscher CD, Moldenhauer SK, Schieber JE, Jacob EK, DiGuardo MA. To Give or Not to Give: RhD Immunoglobulin for an RHD *39 Pregnant Woman with Sickle Cell Disease. Transfus Med Hemother. 2021 Aug; 48(4):244-249. Epub 2021 Feb 25.
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  16. DiGuardo MA, Davila JI, Jackson RA, Nair AA, Fadra N, Minn KT, Atiq MA, Zarei S, Blommel JH, Knight SM, Jen J, Eckloff BW, Voss JS, Rumilla KM, Kerr SE, Lam-Himlin DM, Bellizzi AM, Graham RP, Kipp BR, Jenkins RB, Halling KC. RNA-Seq Reveals Differences in Expressed Tumor Mutation Burden in Colorectal and Endometrial Cancers with and without Defective DNA-Mismatch Repair. J Mol Diagn. 2021 May; 23(5):555-564. Epub 2021 Feb 04.
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  17. Baig NA, Dukek BA, Falbo DK, Wakefield LL, DiGuardo MA, Bobr A, Kreuter JD, Gandhi MJ. Daratumumab interference in flow cytometric anti-granulocyte antibody testing can be overcome using non-human blocking antibodies. Vox Sang. 2021 Jan; 116 (1):116-122 Epub 2020 Aug 14
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  18. DiGuardo MA, Kester SJ, Mahaffey VJ, Hammel SA, Heaser KK, Hofich CD, Tauscher CD, Kerr SE, Oliveira JL, Jacob EK, Moyer AM. Does Transfusion of Red Blood Cells Impact Germline Genetic Test Results? J Pers Med. 2020 Dec 09; 10(4).
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  19. Horton RK, Zuccarelli MD, Wakefield LL, DiGuardo MA, Gandhi MJ, Juskewitch JE. False-negative solid-phase platelet crossmatch results due to prozone phenomenon. Transfusion. 2020 Dec; 60 (12):3055-3059 Epub 2020 Oct 13
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  20. Berry D, DiGuardo M, Mo YD, Wehrli G. Anti-D from alloimmunization versus RhIG: detective work in the blood bank and transfusion medicine services. Transfusion. 2018 Nov; 58 (11):2490-2494 Epub 2018 Sept 19
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  21. Bassaganya-Riera J, DiGuardo M, Climent M, Vives C, Carbo A, Jouni ZE, Einerhand AW, O'Shea M, Hontecillas R. Activation of PPARgamma and delta by dietary punicic acid ameliorates intestinal inflammation in mice. Br J Nutr. 2011 Sep; 106 (6):878-86 Epub 2011 May 31
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  22. Bassaganya-Riera J, DiGuardo M, Viladomiu M, de Horna A, Sanchez S, Einerhand AW, Sanders L, Hontecillas R. Soluble fibers and resistant starch ameliorate disease activity in interleukin-10-deficient mice with inflammatory bowel disease. J Nutr. 2011 Jul; 141 (7):1318-25 Epub 2011 May 11
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  23. Bourcier ME, Sherrod A, DiGuardo M, Vinik AI. Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases. J Clin Endocrinol Metab. 2009 Sep; 94 (9):3157-62 Epub 2009 June 30
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  24. Hontecillas R, O'Shea M, Einerhand A, Diguardo M, Bassaganya-Riera J. Activation of PPAR gamma and alpha by punicic acid ameliorates glucose tolerance and suppresses obesity-related inflammation. J Am Coll Nutr. 2009 Apr; 28 (2):184-95
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  25. Hontecillas R, Diguardo M, Duran E, Orpi M, Bassaganya-Riera J. Catalpic acid decreases abdominal fat deposition, improves glucose homeostasis and upregulates PPAR alpha expression in adipose tissue. Clin Nutr. 2008 Oct; 27 (5):764-72 Epub 2008 Sept 07
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