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Annalise N. Larson

  1. Orthopedic Surgeon

Location

  1. Rochester, Minnesota

Languages

English

Appointments

A. Noelle Larson, M.D., is a pediatric orthopedic surgeon who helps children with spinal conditions such as scoliosis. She and her team use innovative techniques such as low-dose imaging and intraoperative computer-guided navigation to provide better options for pediatric patients.

Dr. Larson is a leading expert who is renowned for using new approaches to scoliosis surgery that preserve spinal motion and growth. She has led several research studies evaluating vertebral body tethering and posterior dynamic distraction. Under these protocols, she performed the first surgeries in the United States for three non-fusion scoliosis devices under FDA protocols. She is also leading efforts to develop tools to help families understand the risks and benefits of new surgical techniques, so they can make informed decisions when deciding which approach is best for their child.

In a further commitment to research and evidence-based medicine, Dr. Larson serves as Research Council Chair for the Pediatric Orthopedic Society of North America and sits on the POSNA/Scoliosis Research Society Pediatric Device Task Force. She also holds leadership positions in the Pediatric Spine Study Group and Harms Study Group. She has authored over 180 peer-reviewed articles and is a Professor in the Department of Orthopedic Surgery at Mayo Clinic. Additionally, Dr. Larson serves as Division Chair for Community Orthopedics.

  1. Mehta cast
  2. Pediatric cervical spine surgery
  3. Scoliosis surgery
  4. Spinal fusion
  5. Vertebral body tethering
  • Scoliosis
  • Pediatric hip deformity and hip dysplasia
  • Pediatric foot deformity
  • Mehta casting for scoliosis
  • Neuromuscular disease
  • Growth plate injuries
  • Hip dysplasia
  • Patient safety/comparative effectiveness research
  • Decision analysis modeling/clinical outcomes/clinical trials
  1. 2010
    Fellow - Edwards Fellowship in Pediatric Orthopaedics and ScoliosisTexas Scottish Rite Hospital for Children
  2. 2009
    ResidentOrthopedic Surgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. 2009
    Resident - Orthopedic Surgery Residency ProgramMayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic College of Medicine and Science
  4. 2004
    MDUniversity of Washington School of Medicine
  5. 1999
    BS - PhysicsStanford University

Certifications

  1. 2013
    Orthopedic SurgeryAmerican Board of Orthopaedic Surgery

Awards and honors

  1. 2026
    Minnesota Monthly 2026 Legacy of Excellence in HealthcareMinnesota Top Doctors
  2. 2026
    IMAST Innovation AwardScoliosis Research Society
  3. 2025
    Minnesota Monthly 2025 Top Doctors Award Minnesota Top Doctors
  4. 2025
    Special Effort AwardPediatric Orthopedic Society of North America
  5. 2024
    Coventry Award Mayo Clinic Coventry Committee
  6. 2024
    Minnesota Monthly 2024 Top Doctors Minnesota Monthly's Top Doctors
  7. 2024
    Patient Experience Award - 2023 Top PerformerTop Performing Provider Patient Experience Award
  8. 2023
    Morris Duhaime Award in Orthopaedic EngineeringQuebec Scoliosis Society
  9. 2023
    Prix Jean-Dansereau Engineering AwardQuebec Scoliosis Society
  10. 2023
    Minnesota Monthly 2023 Top DoctorMinnesota Monthly's Top Doctors
  11. 2023
    Award Nominated Paper: Deep Learning Classification of Spinal Radiographs for Use in Large Scale Imaging Registries Pediatric Orthopedic Society of North America
  12. 2022
    Moe Award for Best Basic Science Poster57th Annual Meeting, Scoliosis Research Society
  13. 2022
    2022 National Health Information Gold Award - What You Need To Know About Scoliosis (MC2462-12)National Health Information Awards, Health Information Resource Center (HIRC)
  14. 2022
    2022 National Health Information Bronze Award - Vertebral Body Tethering (VBT): Surgery to Treat Scoliosis (MC2462-09)National Health Information Awards, Health Information Resource Center (HIRC)
  15. 2022
    Minnesota Monthly 2022 Top Doctors Minnesota Monthly's Top Doctors
  16. 2021
    Morris Duhaime Award in Orthopaedic Engineering Quebec Scoliosis Society
  17. 2020
    2020 National Health Information Bronze Award - Spinal Fusion Surgery for Neuromuscular ScoliosisNational Health Information Awards, Health Information Resource Center (HIRC)
  18. 2020
    2020 POSNA Best Clinical Award Paper: Prospective Randomized Controlled Trial of Implant Density in AIS: Results of the Minimize Implants Maximize Outcomes StudyPediatric Orthopedic Society of North America
  19. 2019
    Hibbs Award Basic Research Nominee, "Are Serum Ion Levels Elevated in Pediatric Patients with Spinal Implants vs. Controls?"Scoliosis Research Society
  20. 2019
    Hibbs Award Clinical Research Nominee, "Prospective Randomized Controlled Trial of Implant Density in AIS: Results of the Minimize Implants Maximize Outcomes Study"Scoliosis Research Society
  21. 2019
    Best Trauma Paper, "Does time to treatment of pediatric femoral shaft fractures impact clinical outcomes?" Pediatric Orthopaedic Society of North America
  22. 2019
    OREF Award Paper, "Is the axial spinal cord classification predictive of intraoperative neurologic alert for pediatric scoliosis patients? A validation study."Minnesota Orthopaedic Society
  23. 2019
    2019 National Health Information Award -- My Scoliosis Story (MC2462-07, Mayo patient education)Mayo Clinic
  24. 2019
    Pediatric Vertebral Body Anterior Tethering SystemVentures Innovation Program
  25. 2017
    Hibbs Award Basic Research Nominee, "Molecular Characterization of Intervertebral Disc Tissue by Next Generation RNA Sequencing"Scoliosis Research Society
  26. 2017
    Minnesota Monthly 2017 Top DoctorsMinnesota Monthly's Top Doctors
  27. 2016
    2016 National Health Information Award: Merit Award Winner -- Leg Length Discrepancy and Angular Deformity (MC7630, patient education)Mayo Clinic
  28. 2015
    Hibbs Award Clinical Research Nominee, "Cervical Spine Disease Common after Pediatric Treatment of AIS at Mean 30-Year Follow-Up" Scoliosis Research Society
  29. 2015
    2015 POSNA Traveling Fellowship to the Pan PacificPediatric Orthopaedic Society of North America
  30. 2014
    Hibbs Award Clinical Research Nominee, "Minimum 20-Year Radiographic Outcomes for Treatment of Adolescent Idiopathic Scoliosis: Preliminary Results from a Novel Cohort of US Patients"Scoliosis Research Society
  31. 2013
    Top Manuscript ReviewerClinical Orthopaedics and Related Research
  32. 2011
    Award poster, "Management of the Pulseless Supracondular Humerus Fracture: Is Vascular Exploration Necessary?" Pediatric Orthopaedic Society of North America
  33. 2010
    T. Boone Pickens Award for Excellence in Spine ResearchTexas Scottish Rite Hospital for Children
  34. 2009
    Joseph M. Janes Award for Compassion, Competence, and Devotion to the SpecialtyDepartment of Orthopedic Surgery
  35. 2009
    OREF Award presentation, "Ischial Spine Projection Reveals a High Rate of Acetabular Retroversion in Perthes Disease"Minnesota Orthopaedic Society
  36. 2004
    Honors in Medicine, M.D.University of Washington School of Medicine
  37. 2004
    Alpha Omega Alpha Honor SocietyUniversity of Washington School of Medicine
  38. 1999
    Honors in Physics, B.S.Stanford University
  39. 1999
    Firestone Medal for Excellence in Undergraduate Research, awarded to top physics honor thesisStanford University

Professional memberships

  1. 2025 - present
    Committee ChairScoliosis Research Society
  2. 2025 - present
    Committee ChairPediatric Orthopedic Society of North America
  3. 2025 - 2027
    ChairPediatric Spine Study Group
  4. 2024 - 2025
    Education Committee ChairScoliosis Research Society
  5. 2022 - 2025
    Research ChairPediatric Orthopaedic Society of North America
  6. 2021 - 2022
    Principal Researcher MemberPediatric Spine Study Group
  7. 2020 - present
    Nominating CommitteePediatric Orthopedic Society of North America
  8. 2020 - present
    Research CouncilPediatric Spine Study Group
  9. 2020 - present
    Nominating CommitteeScoliosis Research Society
  10. 2019 - 2021
    LeaderPediatric Spine Study Group
  11. 2019 - present
    MemberMayo Clinic Orthopedic Research Executive Committee (OREC)
  12. 2019 - present
    FellowAmerican Orthopedic Association
  13. 2019 - 2024
    Director of Grand RoundsDepartment of Orthopedic Surgery
  14. 2019 - 2022
    Research Committee ChairPediatric Orthopaedic Society of North America
  15. 2019 - present
    Education CommitteePediatric Orthopaedic Society of North America
  16. 2018 - present
    MemberHarms Study Group
  17. 2018 - present
    Research CommitteePediatric Orthopaedic Society of North America
  18. 2017 - present
    MemberFinance Committee, Department of Orthopedic Surgery
  19. 2016 - 2018
    Board MemberPediatric Orthopaedic Society of North America
  20. 2016 - present
    FellowScoliosis Research Society
  21. 2015 - present
    MemberStaff Recruitment Committee, Department of Orthopedic Surgery
  22. 2015 - present
    LeadKnowledge Content Board - Orthopedics, AskMayoExpert
  23. 2015 - present
    Active MemberMid-America Orthopaedic Association
  24. 2014 - 2016
    Board MemberMinnesota Orthopaedic Society (MOS)
  25. 2014 - present
    FellowAmerican Academy of Orthopaedic Surgeons
  26. 2013 - present
    MemberSelection Committee, Research Fellows Award Program, Orthopedic Research Committee
  27. 2013 - present
    MemberKelly Research Award Selection Committee, Orthopedic Research Committee, Department of Orthopedic Surgery
  28. 2013 - present
    Meeting DirectorPerry Initiative, Ruth Jackson Orthopaedic Society
  29. 2013 - 2015
    MemberOrthopedic Content Reviewer, Ask Mayo Expert; Orthopedic Content Reviewer
  30. 2013 - 2015
    MemberEvidence-Based Medicine Spondylolisthesis Task Force, Scoliosis Research Society
  31. 2013 - 2014
    MemberProgram Committee, Scoliosis Research Society
  32. 2013 - present
    MemberDatabase Task Force, Orthopedic Research Committee, Department of Orthopedic Surgery
  33. 2013 - present
    Meeting Chair2014 Annual Meeting Cha, Minnesota Orthopedic Society Annual Meeting, Minneapolis, MN
  34. 2013 - present
    Principal InvestigatorMayo Site Principal Investigator, Children's Spine Study Group
  35. 2012 - present
    MemberKelly Research Award Selection Committee, Orthopedic Research Committee, Department of Orthopedic Surgery
  36. 2012 - 2018
    MemberInternational Perthes Study Group
  37. 2012 - 2016
    Candidate MemberScoliosis Research Society
  38. 2012 - 2014
    MemberM&M Committee, Scoliosis Research Society
  39. 2012 - 2014
    MemberResearch Committee, Scoliosis Research Society
  40. 2012 - present
    MemberOrthopedic Research Committee, Department of Orthopedic Surgery
  41. 2012 - present
    MemberMayo Orthopedic Department Internet Task Force, Department of Orthopedic Surgery
  42. 2012 - present
    MemberChildren's Spine Study Group
  43. 2012 - present
    MemberQuality, Safety Value Committee, Pediatric Orthopaedic Society of North America
  44. 2011 - present
    MemberOrthopedic Education Committee, Department of Orthopedic Surgery
  45. 2011 - present
    MemberMinnesota Orthopaedic Society
  46. 2011 - present
    MemberZumbro Valley Medical Society, Minnesota Medical Association
  47. 2011 - present
    Co-Principal InvestigatorMinimize Implants Maximize Outcomes Study Group
  48. 2010 - 2015
    MemberYoung Surgeon's Study Group
  49. 2008 - present
    MemberEmerging Leaders Program, American Orthopaedic Association
  50. 2007 - present
    Resident MemberMayo Clinic International Health Program
  51. 2006 - 2009
    Resident MemberOrthopedic Research Review Committee, Department of Orthopedic Surgery
  52. 2006 - 2009
    Resident MemberOrthopedic Education Committee, Department of Orthopedic Surgery
  53. 2004 - present
    MemberMinnesota Medical Association
  54. 2003 - present
    MemberRuth Jackson Orthopaedic Society

Publications

Research activities

See a description of research activities.

PST-20226411